|
KMID : 0861420110150020021
|
|
Korean Journal of Nuclear Medicine Technology
2011 Volume.15 No. 2 p.21 ~ p.25
|
|
|
The study on Standard Uptake Value(SUV) change according to time input difference in PET/CT scan
|
|
Kim Kyeong-Sik
Lee Joo-Young
Jung Woo-Young
Kim Jung-Seon
|
|
|
Abstract
|
|
|
Purpose:18F-FDG Fusion Whole Body PET scan is performed approximately 1 hour after injecting 18F-FDG. At
this point in the injection procedure, as a tool of the criteria of time input, time of clocks or computers can be used
and in the scan procedure, time of workstation can be used. In case that synchronized time input is not done in the
injection and scan procedures for PET scan, time error from injection to scan can occur. This time error may
affect Standard Uptake Value (SUV) being used as quantitative assessment. Therefore, in this study, we analyzed
the change of SUV according to time input difference and necessity of time synchronization. Materials and
Methods:The analysis was performed to 30 patients (54.8±15.5 years old) who examined 18F-FDG Fusion
Whole Body PET scan in Department of nuclear medicine, Asan Medical Center from December 2009 to
February 2010. To observe the change of SUV according to time input difference, the image was reconstructed
and analyzed by artificially changing time difference of 1, 2, 3, 5, 10, 20 min against the same patients based on
60 minutes.
Results:SUV of the image that reconstructed the images of 30 patients by giving intervals of 1, 2, 3,
5, 10, 20 min respectively and the image that entered original time was compared and analyzed through paired
t-test. Based on 0 minute, mean SUV of aorta was changed by 0.3, 1.1, 1.4, 3.2, 4.7, 12.5% respectively and there
was no statistically significant difference in 1, 2 minutes (p>0.05) but there was significant difference in 3, 5, 10,
20 min (p<0.05). The changes of SUVavg of liver were 1.6, 2.5, 3.0, 4.2, 6.6, 12.8% in 1, 2, 3, 5, 10, 20 min
respectively and the changes of SUVmax of primary lesion were 1.0, 1.5, 2.2, 3.5, 6.6, 12.8% respectively
(p<0.05).
Conclusion:Errors may occur in the process of measuring or recording variables affecting SUV such
as height and weight of patients, 18F-FDG dose, Emission scan start time etc. and as these errors are more, the
accurate assessment of SUV is interfered. Therefore, in order to assess SUV more accurately, it is thought that
efforts to minimize these errors should be made. Of these efforts, time synchronization will be a cornerstone for
accurate scanning.
|
|
|
KEYWORD
|
|
|
Standard uptake value (SUV), Time synchronization, PET/CT
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|